DEVELOPMENT AND VALIDATION OF NOMOGRAM TO PREOPERATIVELY PREDICT INTRAOPERATIVE CEREBROSPINAL FLUID LEAKAGE IN ENDOSCOPIC PITUITARY SURGERY: A RETROSPECTIVE COHORT STUDY

BackgroundPituitary adenomas (PAs) are the most common tumor of the sellar region.PA resection is the preferred treatment for patients with clear indications for surgery.Intraoperative cerebrospinal fluid (iCSF) leakage is a major complication of PA resection flexcon reverse osmosis water storage tank surgery.Risk factors for iCSF leakage have been